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consist of body plans, which scientists have used to classify all life forms, and all significant animal phyla had appeared by the Cambrian Period’s end. The Cambrian Explosion has been difficult to explain and there is still great controversy and many unanswered questions, and it has also been difficult to explain why significant change stopped the explosion. Once the basic body plans appeared and biomes were filled, new plans never appeared again. Why did all fundamental change stop? The emerging view is the same for why complex life with and never changed since then. Not only could innovation confer great benefits, but , further travel along the developmental path made it continually less feasible to backtrack, start over, and take another path, or choose a fundamentally different path. The history of life’s choices was reflected in organisms in several ways, and the source of that inertia began to be understood when biology and chemistry at the cellular and subcellular levels were investigated, particularly after DNA was sequenced and studied. The fact that have not significantly changed in several hundred million years points to the issue. Hox genes have not changed because they control key developmental steps in embryonic development. Not only do Hox genes work, there are no practical ways to significantly change them, as they lay the animal’s structural foundation. Hox genes are called regulatory genes, and the nature of seems to be why animals have not fundamentally changed since the Cambrian Explosion.

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A free radical is an atom, molecule, or ion with an unpaired valence electron or an unfilled shell, and thus seeks to capture an electron. The used to create ATP in a mitochondrion leaks electrons, which creates free radicals, which will take that electron from wherever they can get it. creates some of the most dangerous free radicals, particularly the . The more hydroxyl radicals created, the more damage inflicted on neighboring molecules. Another free radical created by that electron leakage is , which can be neutralized by , but there is no avoiding the damage produced by the hydroxyl radical. Those kinds of free radicals are called (“ROS”). ROS are not universally deleterious to life processes, but if their production spins out of control, the oxidative stress inflicted by the ROS can cripple biological structures. ROS damage can cause programmed cell death, called , which is a maintenance process for complex life. Antioxidants are one way that organisms defend against oxidative stress, and is a standard antioxidant. Antioxidants usually serve multiple purposes in cellular chemistry, and antioxidant supplements generally do not work as advertised. They not only do not target the reactions that might be beneficial to prevent, but they can interfere with reactions that are necessary for life processes. Antioxidant supplements are blunt instruments that can cause more harm than good.

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Society has really take advantage of the quality and put forth a great effort to answer questions for life before chemistry.

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The Triassic began hot and ended hot, and the Jurassic and Cretaceous were also hot, so staying warm was not a significant issue for dinosaurs. stayed cool by becoming aquatic, and for land-based dinosaurs, features such as plates apparently replaced the sails of for both heating and cooling, and like the synapsid sail, those plates may have also been used for display. Also, like the cliché, many large herbivorous dinosaurs lived near cooling swamps, although the issue has been controversial. Cooling swamps and protective water holes that we see in the tropics today were a major aspect of Mesozoic landscapes. But the thermoregulatory aspect that most work is directed toward today is how dinosaurs kept warm. There is compelling evidence that dinosaurs regulated their body temperature in myriad ways, including internal chemistry. All bipedal animals today are endotherms and they all have four-chambered hearts, as dinosaurs did. , dinosaurs living near the poles (, ), and of dinosaur bones all support the idea that , but one of the more intriguing areas is that of . Like tree rings, bones have seasonal growth rings and they have been read for many dinosaur fossils. They have been used to determine dinosaurian life expectancies. could live to be about 30, giant could live to be 50, and smaller dinosaurs, as with smaller mammals, lived shorter lives. The tiny ones only lived three-to-four years and the mid-sized ones lived seven-to-fifteen years. Growth rates also provide thermoregulation evidence. Tyrannosaurs had juvenile growth spurts and largely stopped growing as adults, and sauropods had growth rates equivalent to today’s whales, which are Earth’s fastest growing animals. But there is also evidence of ectothermic dynamics. The great size of dinosaurs would have led to relatively easy ways to stay warm, as large animals have a greater mass-to-surface area ratio, like the way in which . Also, in the generally hot Mesozoic times, staying warm would have been fairly easy, particularly for huge dinosaurs.

With the above limitations acknowledged, this essay will explore the earthly journeys of life and humanity, and energy’s role in them.

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A great potential pitfall is judging the 99.9+% of humanity that cannot or will refuse to comprehend this essay’s message, and it is almost always their victim-oriented mindset that is their barrier to comprehension. People cannot be talked out of thinking like victims; only experience can shatter their paradigm. Brian’s question regarding whether . I consider humanity a semi-sentient species; the potential for sentience is there, but is rarely realized, as people traded their sentience for the promise of security in a world of scarcity.

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